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Akt Inhibitor Akt-IV Blocks Virus Replication through an Akt-Independent Mechanism

Many viruses activate the phosphatidylinositol 3′-kinase (PI3k)/Akt intracellular signaling pathway to promote viral replication. We have analyzed whether a rapidly replicating rhabdovirus, vesicular stomatitis virus (VSV), requires the PI3k/Akt signaling pathway for its replication. Through the use...

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Bibliografiske detaljer
Main Authors: Dunn, Ewan F., Fearns, Rachel, Connor, John H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772702/
https://ncbi.nlm.nih.gov/pubmed/19740993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01092-09
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