Cidofovir Inhibits Genome Encapsidation and Affects Morphogenesis during the Replication of Vaccinia Virus

Cidofovir (CDV) is one of the most effective antiorthopoxvirus drugs, and it is widely accepted that viral DNA replication is the main target of its activity. In the present study, we report a detailed analysis of CDV effects on the replicative cycles of distinct vaccinia virus (VACV) strains: Canta...

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Главные авторы: Jesus, Desyreé Murta, Costa, Lilian T., Gonçalves, Daniela L., Achete, Carlos Alberto, Attias, Marcia, Moussatché, Nissin, Damaso, Clarissa R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
Предметы:
Genome Replication and Regulation of Viral Gene Expression
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772695/
https://ncbi.nlm.nih.gov/pubmed/19726515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01061-09
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