Cidofovir Inhibits Genome Encapsidation and Affects Morphogenesis during the Replication of Vaccinia Virus

Cidofovir (CDV) is one of the most effective antiorthopoxvirus drugs, and it is widely accepted that viral DNA replication is the main target of its activity. In the present study, we report a detailed analysis of CDV effects on the replicative cycles of distinct vaccinia virus (VACV) strains: Canta...

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Main Authors: Jesus, Desyreé Murta, Costa, Lilian T., Gonçalves, Daniela L., Achete, Carlos Alberto, Attias, Marcia, Moussatché, Nissin, Damaso, Clarissa R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Genome Replication and Regulation of Viral Gene Expression
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772695/
https://ncbi.nlm.nih.gov/pubmed/19726515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01061-09
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