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Role of Deletion Located between the Intermediate and Middle Regions of the Helicobacter pylori vacA Gene in Cases of Gastroduodenal Diseases

The vacuolating cytotoxin gene of Helicobacter pylori, vacA, induces cytoplasmic vacuolation in gastric epithelial cells. Recently, the vacA intermediate (i) region, which is located between the signal (s) and middle (m) regions, was identified as a third polymorphic determinant of vacA activity. In...

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Bibliografiske detaljer
Main Authors: Ogiwara, Hiroaki, Sugimoto, Mitsushige, Ohno, Tomoyuki, Vilaichone, Ratha-Korn, Mahachai, Varocha, Graham, David Y., Yamaoka, Yoshio
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772588/
https://ncbi.nlm.nih.gov/pubmed/19726606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00887-09
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