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Role of Deletion Located between the Intermediate and Middle Regions of the Helicobacter pylori vacA Gene in Cases of Gastroduodenal Diseases

The vacuolating cytotoxin gene of Helicobacter pylori, vacA, induces cytoplasmic vacuolation in gastric epithelial cells. Recently, the vacA intermediate (i) region, which is located between the signal (s) and middle (m) regions, was identified as a third polymorphic determinant of vacA activity. In...

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Main Authors: Ogiwara, Hiroaki, Sugimoto, Mitsushige, Ohno, Tomoyuki, Vilaichone, Ratha-Korn, Mahachai, Varocha, Graham, David Y., Yamaoka, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772588/
https://ncbi.nlm.nih.gov/pubmed/19726606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00887-09
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