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A Unique 45-Amino-Acid Region in the Toprim Domain of Plasmodium falciparum Gyrase B Is Essential for Its Activity

DNA gyrase is the only topoisomerase that can introduce negative supercoils into the DNA at the cost of ATP hydrolysis. Some but not all the steps of the topoisomerization reaction are understood clearly for both eukaryotic topoII and DNA gyrase. This study is an attempt to understand whether the B...

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Bibliografiske detaljer
Main Authors: Dar, Ashraf, Prusty, Dhaneswar, Mondal, Neelima, Dhar, Suman K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772398/
https://ncbi.nlm.nih.gov/pubmed/19700639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00149-09
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