Goa1p of Candida albicans Localizes to the Mitochondria during Stress and Is Required for Mitochondrial Function and Virulence

Using a Tn7 transposon library of Candida albicans, we have identified a mutant that exhibited sensitivity in drop plate assays to oxidants such as menadione and hydrogen peroxide. To verify the role of the mutated gene in stress adaptation, null mutants were constructed and phenotypically character...

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Hauptverfasser: Bambach, Adrienne, Fernandes, Mariana P., Ghosh, Anup, Kruppa, Michael, Alex, Deepu, Li, Dongmei, Fonzi, William A., Chauhan, Neeraj, Sun, Nuo, Agrellos, Orlando A., Vercesi, Anibal E., Rolfes, Ronda J., Calderone, Richard
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772395/
https://ncbi.nlm.nih.gov/pubmed/19717740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00066-09
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