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The Ssk1p Response Regulator and Chk1p Histidine Kinase Mutants of Candida albicans Are Hypersensitive to Fluconazole and Voriconazole

Hypersensitivity to the triazoles fluconazole and voriconazole associated with two-component signal transduction proteins has not been reported in Candida albicans. Herein, we show that strains of C. albicans lacking the response regulator Ssk1p or the Chk1p histidine kinase signal transduction prot...

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Detalhes bibliográficos
Main Authors: Chauhan, Neeraj, Kruppa, Michael, Calderone, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043284/
https://ncbi.nlm.nih.gov/pubmed/17664325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00929-07
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