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Two Distinct Major Facilitator Superfamily Drug Efflux Pumps Mediate Chloramphenicol Resistance in Streptomyces coelicolor

Chloramphenicol, florfenicol, and thiamphenicol are used as antibacterial drugs in clinical and veterinary medicine. Two efflux pumps of the major facilitator superfamily encoded by the cmlR1 and cmlR2 genes mediate resistance to these antibiotics in Streptomyces coelicolor, a close relative of Myco...

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Autori principali: Vecchione, James J., Alexander, Blair, Sello, Jason K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772354/
https://ncbi.nlm.nih.gov/pubmed/19687245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00853-09
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