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Two Distinct Major Facilitator Superfamily Drug Efflux Pumps Mediate Chloramphenicol Resistance in Streptomyces coelicolor

Chloramphenicol, florfenicol, and thiamphenicol are used as antibacterial drugs in clinical and veterinary medicine. Two efflux pumps of the major facilitator superfamily encoded by the cmlR1 and cmlR2 genes mediate resistance to these antibiotics in Streptomyces coelicolor, a close relative of Myco...

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Bibliografski detalji
Glavni autori: Vecchione, James J., Alexander, Blair, Sello, Jason K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772354/
https://ncbi.nlm.nih.gov/pubmed/19687245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00853-09
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