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PEG-PE micelles loaded with paclitaxel and surface-modified by a PBR-ligand: synergistic anticancer effect

[Image: see text] Selective ligands to the Peripheral Benzodiazepine Receptor (PBR) may induce apoptosis and cell cycle arrest. An over-expression of PBR in certain cancers allowed us to consider the use of highly selective ligands to PBR for receptor-mediated drug targeting to tumors. With this in...

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Detalhes bibliográficos
Main Authors: Musacchio, Tiziana, Laquintana, Valentino, Latrofa, Andrea, Trapani, Giuseppe, Torchilin, Vladimir P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772116/
https://ncbi.nlm.nih.gov/pubmed/19718800
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