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Downstream signals for MyD88-mediated phagocytosis of B. burgdorferi can be initiated by TRIF and are dependent upon PI3K

We previously have shown that MyD88 is important for uptake of B. burgdorferi by bone marrow derived macrophages (BMDMs). The mechanism by which MyD88 is involved in uptake of B. burgdorferi is currently is not well characterized. Here, we report that MyD88-mediated defect in the phagocytosis of B....

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Autores principales: Shin, Ok S., Miller, Lloyd S., Modlin, Robert L., Akira, Shizuo, Uematsu, Satoshi, Hu, Linden T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772066/
https://ncbi.nlm.nih.gov/pubmed/19542460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900724
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