MVA-Based H5N1 Vaccine Affords Cross-Clade Protection in Mice against Influenza A/H5N1 Viruses at Low Doses and after Single Immunization

Human infections with highly pathogenic avian influenza viruses of the H5N1 subtype, frequently reported since 2003, result in high morbidity and mortality. It is feared that these viruses become pandemic, therefore the development of safe and effective vaccines is desirable. MVA-based H5N1 vaccines...

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Autores principales: Kreijtz, Joost H. C. M., Suezer, Yasemin, de Mutsert, Gerrie, van Amerongen, Geert, Schwantes, Astrid, van den Brand, Judith M. A., Fouchier, Ron A. M., Löwer, Johannes, Osterhaus, Albert D. M. E., Sutter, Gerd, Rimmelzwaan, Guus F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771904/
https://ncbi.nlm.nih.gov/pubmed/19915662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007790
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