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The Invader(®) assay for SNP genotyping
The Invader(®) assay uses a structure-specific flap endonuclease (FEN) to cleave a three-dimensional complex formed by hybridization of allele-specific overlapping oligonucleotides to target DNA containing a single nucleotide polymorphism (SNP) site. Annealing of the oligonucleotide complementary to...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2771639/ https://ncbi.nlm.nih.gov/pubmed/15829241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2004.08.016 |
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