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Computational tradeoffs in multiplex PCR assay design for SNP genotyping

BACKGROUND: Multiplex PCR is a key technology for detecting infectious microorganisms, whole-genome sequencing, forensic analysis, and for enabling flexible yet low-cost genotyping. However, the design of a multiplex PCR assays requires the consideration of multiple competing objectives and physical...

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Autores principales: Rachlin, John, Ding, Chunming, Cantor, Charles, Kasif, Simon
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190169/
https://ncbi.nlm.nih.gov/pubmed/16042802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-6-102
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