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Multiple roles of HDAC inhibition in neurodegenerative conditions

Histone deacetylases (HDACs) play a key role in homeostasis of protein acetylation in histones and other proteins and in regulating fundamental cellular activities such as transcription. Imbalances in protein acetylation levels and dysfunctions in transcription are associated with a wide variety of...

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Hlavní autoři: Chuang, De-Maw, Leng, Yan, Marinova, Zoya, Kim, Hyeon-Ju, Chiu, Chi-Tso
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771446/
https://ncbi.nlm.nih.gov/pubmed/19775759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2009.06.002
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