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Multiple roles of HDAC inhibition in neurodegenerative conditions
Histone deacetylases (HDACs) play a key role in homeostasis of protein acetylation in histones and other proteins and in regulating fundamental cellular activities such as transcription. Imbalances in protein acetylation levels and dysfunctions in transcription are associated with a wide variety of...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2771446/ https://ncbi.nlm.nih.gov/pubmed/19775759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2009.06.002 |
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