Diminished Macrophage Apoptosis and Reactive Oxygen Species Generation after Phorbol Ester Stimulation in Crohn's Disease

BACKGROUND: Crohn's Disease (CD) is a chronic relapsing disorder characterized by granulomatous inflammation of the gastrointestinal tract. Although its pathogenesis is complex, we have recently shown that CD patients have a systemic defect in macrophage function, which results in the defective...

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Detalhes bibliográficos
Main Authors: Palmer, Christine D., Rahman, Farooq Z., Sewell, Gavin W., Ahmed, Afshan, Ashcroft, Margaret, Bloom, Stuart L., Segal, Anthony W., Smith, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771353/
https://ncbi.nlm.nih.gov/pubmed/19907654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007787
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