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Apolipoprotein AI tertiary structures determine stability and phospholipid-binding activity of discoidal high-density lipoprotein particles of different sizes

Human high-density lipoprotein (HDL) plays a key role in the reverse cholesterol transport pathway that delivers excess cholesterol back to the liver for clearance. In vivo, HDL particles vary in size, shape and biological function. The discoidal HDL is a 140–240 kDa, disk-shaped intermediate of mat...

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Detalhes bibliográficos
Main Authors: Chen, Bin, Ren, Xuefeng, Neville, Tracey, Jerome, W Gray, Hoyt, David W, Sparks, Daniel, Ren, Gang, Wang, Jianjun
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771295/
https://ncbi.nlm.nih.gov/pubmed/19384992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.101
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