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A Novel Animal Model of Nonalcoholic Steatohepatitis (NASH): Hypoxemia Enhances the Development of NASH

Recent reports described a high incidence of nonalcoholic steatohepatitis (NASH) in patients with obstructive sleep apnea. Accordingly, we hypothesized that recurrent and intermittent hypoxemia plays an important role in the pathogenesis of NASH. Our objective was construction of a practical and acc...

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Detalhes bibliográficos
Main Authors: Takayama, Fusako, Egashira, Toru, Kawasaki, Hiromu, Mankura, Mitsumasa, Nakamoto, Kazuo, Okada, Shigeru, Mori, Akitane
Formato: Artigo
Idioma:Inglês
Publicado em: the Society for Free Radical Research Japan 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771256/
https://ncbi.nlm.nih.gov/pubmed/19902025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.09-29
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