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A Novel Animal Model of Nonalcoholic Steatohepatitis (NASH): Hypoxemia Enhances the Development of NASH

Recent reports described a high incidence of nonalcoholic steatohepatitis (NASH) in patients with obstructive sleep apnea. Accordingly, we hypothesized that recurrent and intermittent hypoxemia plays an important role in the pathogenesis of NASH. Our objective was construction of a practical and acc...

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Autors principals: Takayama, Fusako, Egashira, Toru, Kawasaki, Hiromu, Mankura, Mitsumasa, Nakamoto, Kazuo, Okada, Shigeru, Mori, Akitane
Format: Artigo
Idioma:Inglês
Publicat: the Society for Free Radical Research Japan 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771256/
https://ncbi.nlm.nih.gov/pubmed/19902025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.09-29
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