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A Novel Animal Model of Nonalcoholic Steatohepatitis (NASH): Hypoxemia Enhances the Development of NASH

Recent reports described a high incidence of nonalcoholic steatohepatitis (NASH) in patients with obstructive sleep apnea. Accordingly, we hypothesized that recurrent and intermittent hypoxemia plays an important role in the pathogenesis of NASH. Our objective was construction of a practical and acc...

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Autori principali: Takayama, Fusako, Egashira, Toru, Kawasaki, Hiromu, Mankura, Mitsumasa, Nakamoto, Kazuo, Okada, Shigeru, Mori, Akitane
Natura: Artigo
Lingua:Inglês
Pubblicazione: the Society for Free Radical Research Japan 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771256/
https://ncbi.nlm.nih.gov/pubmed/19902025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.09-29
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