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Simvastatin Inhibits Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E Knockout Mice: possible role of ERK
OBJECTIVE: Abdominal aortic aneurysm (AAA) is a life-threatening disease affecting almost 10% of the population over age 65. Generation of AAAs by infusion of Angiotensin (Ang) II in Apolipoprotein E knockout (ApoE−/−) mice is an animal model which supports an imbalance of the renin-angiotensin syst...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2771227/ https://ncbi.nlm.nih.gov/pubmed/19729613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.192609 |
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