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Fluoro-Julia Olefination as a Mild, High-Yielding Route to α-Fluoro Acrylonitriles

[Image: see text] Synthesis of a novel, stable reagent (1,3-benzothiazol-2-ylsulfonyl)fluoroacetonitrile from readily available ethyl α-(1,3-benzothiazol-2-ylsulfanyl)- α-fluoroacetate is reported. Aldehydes undergo condensations with (1,3-benzothiazol-2-ylsulfonyl)fluoroacetonitrile in the presence...

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Main Authors: del Solar, Maria, Ghosh, Arun K., Zajc, Barbara
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771215/
https://ncbi.nlm.nih.gov/pubmed/18841918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo801235x
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