Defective interaction between Pol2p and Dpb2p, subunits of DNA polymerase epsilon, contributes to a mutator phenotype in Saccharomyces cerevisiae

Most of the prokaryotic and eukaryotic replicative polymerases are multi-subunit complexes. There are several examples indicating that noncatalytic subunits of DNA polymerases may function as fidelity factors during replication process. In this work, we have further investigated the role of Dpb2p, a...

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Hauptverfasser: Jaszczur, Malgorzata, Rudzka, Justyna, Kraszewska, Joanna, Flis, Krzysztof, Polaczek, Piotr, Campbell, Judith L., Fijalkowska, Iwona J., Jonczyk, Piotr
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771212/
https://ncbi.nlm.nih.gov/pubmed/19463834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2009.04.012
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