CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation

Location of embryonic lymph node development is determined by the initial clustering of lymphoid tissue inducer cells. We demonstrate that both CXCL13 and CCL21 attracted E12.5–E14.5 lymphoid tissue inducer cells and that initial clustering exclusively depended on CXCL13. Retinoic acid induced early...

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Autors principals: van de Pavert, Serge A., Olivier, Brenda J., Goverse, Gera, Vondenhoff, Mark F., Greuter, Mascha, Beke, Patrick, Kusser, Kim, Höpken, Uta E., Lipp, Martin, Niederreither, Karen, Blomhoff, Rune, Sitnik, Kasia, Agace, William W., Randall, Troy D., de Jonge, Wouter J., Mebius, Reina E.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771164/
https://ncbi.nlm.nih.gov/pubmed/19783990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1789
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