Retinoic acid inhibits in vivo interleukin-2 gene expression and T-cell activation in mice

Interleukin-2 (IL-2) is an essential cytokine for T-lymphocyte homeostasis. We have previously reported that all-trans retinoic acid (atRA) enhances the secretion of IL-2 from human peripheral blood T cells in vitro, followed by increased proliferation and inhibition of spontaneous cell death. In th...

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Detalhes bibliográficos
Main Authors: Ertesvag, Aase, Austenaa, Liv M I, Carlsen, Harald, Blomhoff, Rune, Blomhoff, Heidi Kiil
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673363/
https://ncbi.nlm.nih.gov/pubmed/18778286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02913.x
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