Murine Pancreatic Beta TC3 Cells Show Greater 2′, 5′-Oligoadenylate Synthetase (2′5′AS) Antiviral Enzyme Activity and Apoptosis Following IFN-α or Poly(I:C) Treatment than Pancreatic Alpha TC3 Cells

Type 1 diabetes is caused by autoimmune destruction of pancreatic beta cells, possibly virus initiated. Virus infection induces alpha-interferon (IFN-α), leading to upregulation of genes encoding double-stranded (ds) RNA-dependent antiviral enzymes 2′, 5′-oligoadenylate synthetase (2′5′AS) and PKR (...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Li, M., Zheng, D. -J., Field, L. L., Bonnevie-Nielsen, V.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771153/
https://ncbi.nlm.nih.gov/pubmed/19888425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/631026
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados