TNFα inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation

Efficient removal of apoptotic cells is essential for resolution of inflammation. Failure to clear dying cells can exacerbate lung injury and lead to persistent inflammation and autoimmunity. Here we show that TNFα blocks apoptotic cell clearance by alveolar macrophages and leads to proinflammatory...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Borges, Valeria M., Vandivier, R. William, McPhillips, Kathleen A., Kench, Jennifer A., Morimoto, Konosuke, Groshong, Steve D., Richens, Tiffany R., Graham, Brian B., Muldrow, Alaina M., Heule, Lea Van, Henson, Peter M., Janssen, William J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2009
Soggetti:
Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770785/
https://ncbi.nlm.nih.gov/pubmed/19648283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90569.2008
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi