TNFα inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation

Efficient removal of apoptotic cells is essential for resolution of inflammation. Failure to clear dying cells can exacerbate lung injury and lead to persistent inflammation and autoimmunity. Here we show that TNFα blocks apoptotic cell clearance by alveolar macrophages and leads to proinflammatory...

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Main Authors: Borges, Valeria M., Vandivier, R. William, McPhillips, Kathleen A., Kench, Jennifer A., Morimoto, Konosuke, Groshong, Steve D., Richens, Tiffany R., Graham, Brian B., Muldrow, Alaina M., Heule, Lea Van, Henson, Peter M., Janssen, William J.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770785/
https://ncbi.nlm.nih.gov/pubmed/19648283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90569.2008
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