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TNF-α inhibition attenuates adverse myocardial remodeling in a rat model of volume overload
Tumor necrosis factor (TNF)-α is a proinflammatory cytokine that has been implicated in the pathogenesis of heart failure. In contrast, we have recently shown that myocardial levels of TNF-α are acutely elevated in the aortocaval (AV) fistula model of heart failure. Based on these observations, we h...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770768/ https://ncbi.nlm.nih.gov/pubmed/19666842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00442.2009 |
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