Cloning, localization, and functional expression of the electrogenic Na(+) bicarbonate cotransporter (NBCe1) from zebrafish

Mutations in the electrogenic Na(+)/nHCO(3)(−) cotransporter (NBCe1, SLC4A4) cause severe proximal renal tubular acidosis, glaucoma, and cataracts in humans, indicating NBCe1 has a critical role in acid-base homeostasis and ocular fluid transport. To better understand the homeostatic roles and prote...

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Main Authors: Sussman, Caroline R., Zhao, Jinhua, Plata, Consuelo, Lu, Jing, Daly, Christopher, Angle, Nathan, DiPiero, Jennifer, Drummond, Iain A., Liang, Jennifer O., Boron, Walter F., Romero, Michael F., Chang, Min-Hwang
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2009
Fag:
Membrane Transporters, Ion Channels, and Pumps
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770747/
https://ncbi.nlm.nih.gov/pubmed/19625604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00679.2008
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