Biochemical properties and base excision repair complex formation of apurinic/apyrimidinic endonuclease from Pyrococcus furiosus

Apurinic/apyrimidinic (AP) sites are the most frequently found mutagenic lesions in DNA, and they arise mainly from spontaneous base loss or modified base removal by damage-specific DNA glycosylases. AP sites are cleaved by AP endonucleases, and the resultant gaps in the DNA are repaired by DNA poly...

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Detalles Bibliográficos
Main Authors: Kiyonari, Shinichi, Tahara, Saki, Shirai, Tsuyoshi, Iwai, Shigenori, Ishino, Sonoko, Ishino, Yoshizumi
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2009
Assuntos:
Genome Integrity, Repair and Replication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770678/
https://ncbi.nlm.nih.gov/pubmed/19734344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp720
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