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Human Pif1 helicase unwinds synthetic DNA structures resembling stalled DNA replication forks
Pif-1 proteins are 5′→3′ superfamily 1 (SF1) helicases that in yeast have roles in the maintenance of mitochondrial and nuclear genome stability. The functions and activities of the human enzyme (hPif1) are unclear, but here we describe its DNA binding and DNA remodeling activities. We demonstrate t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770657/ https://ncbi.nlm.nih.gov/pubmed/19700773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp671 |
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