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Monocytes from Patients with Type 1 Diabetes Spontaneously Secrete Pro-Inflammatory Cytokines Inducing Th17 Cells

Autoimmune diseases including type 1 diabetes (T1D) are thought to have a Th1/Th17 bias. The underlying mechanisms driving the activation and differentiation of these pro-inflammatory T cells are unknown. We examined the monocytes isolated directly from the blood of T1D patients and found they spont...

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Autores principales: Bradshaw, Elizabeth M., Raddassi, Khadir, Elyaman, Wassim, Orban, Tihamer, Gottlieb, Peter A., Kent, Sally C., Hafler, David A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770506/
https://ncbi.nlm.nih.gov/pubmed/19748982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900576
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