Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in Acute Myeloid Leukemia

BACKGROUND: Translocations of the Mixed Lineage Leukemia (MLL) gene occur in a subset (5%) of acute myeloid leukemias (AML), and in mixed phenotype acute leukemias in infancy - a disease with extremely poor prognosis. Animal model systems show that MLL gain of function mutations may contribute to le...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Röhrs, Sonja, Dirks, Wilhelm G, Meyer, Claus, Marschalek, Rolf, Scherr, Michaela, Slany, Robert, Wallace, Andrew, Drexler, Hans G, Quentmeier, Hilmar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770485/
https://ncbi.nlm.nih.gov/pubmed/19835597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-86
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados