Human T cells express CD25 and Foxp3 upon activation and exhibit effector/memory phenotypes without any regulatory/suppressor function

BACKGROUND: Foxp3 has been suggested to be a standard marker for murine Tregs whereas its role as marker for human Tregs is controversial. While some reports have shown that human Foxp3+ T cells had no regulatory function others have shown their role in the inhibition of T cell proliferation. METHOD...

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Bibliographische Detailangaben
Hauptverfasser: Kmieciak, Maciej, Gowda, Madhu, Graham, Laura, Godder, Kamar, Bear, Harry D, Marincola, Francesco M, Manjili, Masoud H
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770477/
https://ncbi.nlm.nih.gov/pubmed/19849846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-7-89
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