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GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b−Gr1− bone marrow progenitor cells into myeloid-derived suppressor cells

Recent reports have shown the involvement of tumor burden as well as GM-CSF in supporting myeloid-derived suppressor cells (MDSC). However, it is not known what progenitor cells may differentiate into MDSC in the presence of GM-CSF, and whether FVBN202 transgenic mouse model of spontaneous breast ca...

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Bibliografiske detaljer
Main Authors: Morales, Johanna K., Kmieciak, Maciej, Knutson, Keith L., Bear, Harry D., Manjili, Masoud H.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095485/
https://ncbi.nlm.nih.gov/pubmed/19898981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-009-0622-8
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