RNA Aptamers Generated against Oligomeric Aβ40 Recognize Common Amyloid Aptatopes with Low Specificity but High Sensitivity

Aptamers are useful molecular recognition tools in research, diagnostics, and therapy. Despite promising results in other fields, aptamer use has remained scarce in amyloid research, including Alzheimer's disease (AD). AD is a progressive neurodegenerative disease believed to be caused by neuro...

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Detalhes bibliográficos
Main Authors: Rahimi, Farid, Murakami, Kazuma, Summers, Jamie L., Chen, Chi-Hong B., Bitan, Gal
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770325/
https://ncbi.nlm.nih.gov/pubmed/19901993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007694
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