RNA Aptamers Generated against Oligomeric Aβ40 Recognize Common Amyloid Aptatopes with Low Specificity but High Sensitivity

Aptamers are useful molecular recognition tools in research, diagnostics, and therapy. Despite promising results in other fields, aptamer use has remained scarce in amyloid research, including Alzheimer's disease (AD). AD is a progressive neurodegenerative disease believed to be caused by neuro...

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Bibliografiske detaljer
Main Authors: Rahimi, Farid, Murakami, Kazuma, Summers, Jamie L., Chen, Chi-Hong B., Bitan, Gal
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770325/
https://ncbi.nlm.nih.gov/pubmed/19901993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007694
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