Visualization and Identification of IL-7 Producing Cells in Reporter Mice

Interleukin-7 (IL-7) is required for lymphocyte development and homeostasis although the actual sites of IL-7 production have never been clearly identified. We produced a bacterial artificial chromosome (BAC) transgenic mouse expressing ECFP in the Il7 locus. The construct lacked a signal peptide an...

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Main Authors: Mazzucchelli, Renata I., Warming, Søren, Lawrence, Scott M., Ishii, Masaru, Abshari, Mehrnoosh, Washington, A. Valance, Feigenbaum, Lionel, Warner, Andrew C., Sims, Davis J., Li, Wen Qing, Hixon, Julie A., Gray, Daniel H. D., Rich, Benjamin E., Morrow, Matthew, Anver, Miriam R., Cherry, James, Naf, Dieter, Sternberg, Lawrence R., McVicar, Daniel W., Farr, Andrew G., Germain, Ronald N., Rogers, Keith, Jenkins, Nancy A., Copeland, Neal G., Durum, Scott K.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2009
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770321/
https://ncbi.nlm.nih.gov/pubmed/19907640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007637
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