Visualization and Identification of IL-7 Producing Cells in Reporter Mice

Interleukin-7 (IL-7) is required for lymphocyte development and homeostasis although the actual sites of IL-7 production have never been clearly identified. We produced a bacterial artificial chromosome (BAC) transgenic mouse expressing ECFP in the Il7 locus. The construct lacked a signal peptide an...

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Bibliografiske detaljer
Main Authors: Mazzucchelli, Renata I., Warming, Søren, Lawrence, Scott M., Ishii, Masaru, Abshari, Mehrnoosh, Washington, A. Valance, Feigenbaum, Lionel, Warner, Andrew C., Sims, Davis J., Li, Wen Qing, Hixon, Julie A., Gray, Daniel H. D., Rich, Benjamin E., Morrow, Matthew, Anver, Miriam R., Cherry, James, Naf, Dieter, Sternberg, Lawrence R., McVicar, Daniel W., Farr, Andrew G., Germain, Ronald N., Rogers, Keith, Jenkins, Nancy A., Copeland, Neal G., Durum, Scott K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770321/
https://ncbi.nlm.nih.gov/pubmed/19907640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007637
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