Caenorhabditis elegans HIM-18/SLX-4 Interacts with SLX-1 and XPF-1 and Maintains Genomic Integrity in the Germline by Processing Recombination Intermediates

Homologous recombination (HR) is essential for the repair of blocked or collapsed replication forks and for the production of crossovers between homologs that promote accurate meiotic chromosome segregation. Here, we identify HIM-18, an ortholog of MUS312/Slx4, as a critical player required in vivo...

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Detaylı Bibliyografya
Asıl Yazarlar: Saito, Takamune T., Youds, Jillian L., Boulton, Simon J., Colaiácovo, Monica P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2009
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770170/
https://ncbi.nlm.nih.gov/pubmed/19936019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000735
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