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Myostatin represses physiological hypertrophy of the heart and excitation–contraction coupling
Although myostatin negatively regulates skeletal muscle growth, its function in heart is virtually unknown. Herein we demonstrate that it inhibits basal and IGF-stimulated proliferation and differentiation and also modulates cardiac excitation–contraction (EC) coupling. Loss of myostatin induced ecc...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Science Inc
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770153/ https://ncbi.nlm.nih.gov/pubmed/19736304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.172544 |
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