Immunisation with a Multivalent, Subunit Vaccine Reduces Patent Infection in a Natural Bovine Model of Onchocerciasis during Intense Field Exposure

Human onchocerciasis, caused by the filarial nematode Onchocerca volvulus, is controlled almost exclusively by the drug ivermectin, which prevents pathology by targeting the microfilariae. However, this reliance on a single control tool has led to interest in vaccination as a potentially complementa...

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Detalhes bibliográficos
Main Authors: Makepeace, Benjamin L., Jensen, Siv Aina, Laney, Sandra J., Nfon, Charles K., Njongmeta, Leo M., Tanya, Vincent N., Williams, Steven A., Bianco, Albert E., Trees, Alexander J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770122/
https://ncbi.nlm.nih.gov/pubmed/19901988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000544
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