Neutralization of Vascular Endothelial Growth Factor Antiangiogenic Isoforms Is More Effective Than Treatment with Proangiogenic Isoforms in Stimulating Vascular Development and Follicle Progression in the Perinatal Rat Ovary

Inhibition of vascular endothelial growth factor A (VEGFA) signal transduction arrests vascular and follicle development. Because antiangiogenic VEGFA isoforms are proposed to block proangiogenic VEGFA isoforms from binding to their receptors, we hypothesized that proangiogenic isoforms promote and...

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Detalhes bibliográficos
Main Authors: Artac, Robin A., McFee, Renee M., Longfellow Smith, Robyn A., Baltes-Breitwisch, Michelle M., Clopton, Debra T., Cupp, Andrea S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770023/
https://ncbi.nlm.nih.gov/pubmed/19605786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.078097
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