Inhibition of Vascular Endothelial Growth Factor Receptor Signal Transduction Blocks Follicle Progression but Does Not Necessarily Disrupt Vascular Development in Perinatal Rat Ovaries

We hypothesized that vascular endothelial growth factor A (VEGFA) angiogenic isoforms and their receptors, FLT1 and KDR, regulate follicular progression in the perinatal rat ovary. Each VEGFA angiogenic isoform has unique functions (based on its exons) that affect diffusibility, cell migration, bran...

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Detalhes bibliográficos
Main Authors: McFee, Renee M., Artac, Robin A., McFee, Ryann M., Clopton, Debra T., Smith, Robyn A. Longfellow, Rozell, Timothy G., Cupp, Andrea S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770022/
https://ncbi.nlm.nih.gov/pubmed/19605787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.078071
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