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Overactive Beta-Catenin Signaling Causes Testicular Sertoli Cell Tumor Development in the Mouse
Overactive WNT/beta-catenin signaling has been found in many forms of cancer in human patients. Mouse models with mutations in different components of the WNT/beta-catenin signaling pathway have been generated to mimic tumorigenesis in humans. Mice with mutations that result in overactive WNT/beta-c...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Society for the Study of Reproduction, Inc.
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770017/ https://ncbi.nlm.nih.gov/pubmed/19553598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.077446 |
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