CRF(1) receptor antagonists attenuate escalated cocaine self-administration in rats

RATIONALE: Previous work suggests a role for stress-related corticotropin-releasing factor (CRF) systems in cocaine dependence. However, the involvement of activation of CRF(1) receptors in rats self-administering cocaine with extended access is unknown. OBJECTIVE: The current study examined whether...

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Hauptverfasser: Specio, Sheila E., Wee, Sunmee, O’Dell, Laura E., Boutrel, Benjamin, Zorrilla, Eric P., Koob, George F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769571/
https://ncbi.nlm.nih.gov/pubmed/17965976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-007-0983-9
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