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Post-translational import of protein into the endoplasmic reticulum of a trypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities

HAT (human African trypanosomiasis), caused by the protozoan parasite Trypanosoma brucei, is an emerging disease for which new drugs are needed. Expression of plasma membrane proteins [e.g. VSG (variant surface glycoprotein)] is crucial for the establishment and maintenance of an infection by T. bru...

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Bibliografiske detaljer
Main Authors: Patham, Bhargavi, Duffy, Josh, Lane, Ariel, Davis, Richard C, Wipf, Peter, Fewell, Sheara W, Brodsky, Jeffrey L, Mensa-Wilmot, Kojo
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769561/
https://ncbi.nlm.nih.gov/pubmed/19196237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20081787
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