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A sequence element that tunes E. coli tRNA(GGC)(Ala) to ensure accurate decoding

Mutating the rare A32-U38 nucleotide pair at the top of the anticodon loop of E. coli tRNA(GGC)(Ala) to a more common U32-A38 pair results in a tRNA that performs almost normally on cognate codons but is unusually efficient in reading near-cognate codons. Pre-steady state kinetic measurements on E....

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Autors principals: Ledoux, Sarah, Olejniczak, Mikołaj, Uhlenbeck, Olke C.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769084/
https://ncbi.nlm.nih.gov/pubmed/19305403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1581
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