Reactive Oxygen Species Decrease cAMP Response Element Binding Protein Expression in Cardiomyocytes via a Protein Kinase D1-Dependent Mechanism That Does Not Require Ser(133) Phosphorylation

Reactive oxygen species (ROS) exert pleiotropic effects on a wide array of signaling proteins that regulate cellular growth and apoptosis. This study shows that long-term treatment with a low concentration of H(2)O(2) leads to the activation of signaling pathways involving extracellular signal-regul...

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Detalhes bibliográficos
Main Authors: Özgen, Nazira, Guo, Jianfen, Gertsberg, Zoya, Danilo, Peter, Rosen, Michael R., Steinberg, Susan F.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769048/
https://ncbi.nlm.nih.gov/pubmed/19620255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.056473
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