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Dual Role of the Second Extracellular Loop of the Cannabinoid Receptor 1: Ligand Binding and Receptor Localization

The seven transmembrane α-helices of G protein-coupled receptors (GPCRs) are the hallmark of this superfamily. Intrahelical interactions are critical to receptor assembly and, for the GPCR subclass that binds small molecules, ligand binding. Most research has focused on identifying the ligand bindin...

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Detalles Bibliográficos
Autores principales: Ahn, Kwang H., Bertalovitz, Alexander C., Mierke, Dale F., Kendall, Debra A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769047/
https://ncbi.nlm.nih.gov/pubmed/19643997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.057356
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