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Hepatic Cytochrome P450 Enzyme Alterations in Humans with Progressive Stages of Nonalcoholic Fatty Liver Disease

Members of the cytochrome P450 (P450) enzyme families CYP1, CYP2, and CYP3 are responsible for the metabolism of approximately 75% of all clinically relevant drugs. With the increased prevalence of nonalcoholic fatty liver disease (NAFLD), it is likely that patients with this disease represent an em...

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Detalles Bibliográficos
Main Authors: Fisher, Craig D., Lickteig, Andrew J., Augustine, Lisa M., Ranger-Moore, James, Jackson, Jonathan P., Ferguson, Stephen S., Cherrington, Nathan J.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769034/
https://ncbi.nlm.nih.gov/pubmed/19651758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.109.027466
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